Table 6. Integrative analysis of cellular activities specifically absent in Shigella strains.

Genes	Encoded function	Cellular activity
prpBCDER	Methylcitrate cycle	Carboxylate degradation
codBA	Cytosine degradation	Pyrimidine salvage pathway
lacY	Lactose permease	Carbohydrate degradation
allD	Allantoin degradation IV	Amine degradation
fiu	Outer membrane receptor for iron-regulated colicin and the siderophore dihydroxybenzoylserine	Outer membrane transport
speG	Spermidine biosynthesis	Polyamine biosynthesis
guaDygfOQ	Guanine salvage	Purine degradation
agaSkbaYagaB	N-acetylgalactosamine (or galactitol) degradation	Carbohydrate degradation
aapQ	ABC transporter of polar amino acids	Amino-acid transport
rbsB	Ribose ABC transporter	Carbohydrate transport
cadBC	Decarboxylation of lysine	Polyamine biosynthesis
ydiF	Acetate CoA transferase	Fatty acid oxidation
yaaJ	Alanine/Glycine transporter	Amino-acid transport