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. 1996 Dec 10;93(25):14632–14636. doi: 10.1073/pnas.93.25.14632

Table 3.

Old introns

Protein Intron position Status
TPI 38 In
TPI 79 Out
TPI 108 Out
TPI 152 In
TPI 181/4 In
TPI 210 In
GST 148/51 In
HEMO 30 Out
HEMO 100 In
ALDOL 266/9 In
PFK 264/6 In
GAPDH 9 In
GAPDH 43 In
GAPDH 75/8/9 In
GAPDH 146/7 Out
PGK 22 In
PGK 91/2/3 In
CUSOD 23/4 Out
HSP70 69 In
ENOL 60/4 Out

A listing of 20 “ancient” introns identified as having matching positions in three out of four groups of vertebrates, invertebrates, plants, or fungi. Introns were considered homologous if they had slid up to four codons. The status column defines their character with respect to the linker regions for 28-Å modules (using the average position for slid introns). Fourteen of the 20 intron positions are within the linker regions rather than the 6.4 expected: χ2 = 13.3, P < 0.0003.