Table 6.
MARS results of the analysis of ACTG data with HDL-c levels as trait and SNPs from ApoCIII, ApoE, EL and HL genes and race/ethnicity as predictors
| Include* | Ignore* | Residualize* | White (n = 317) |
Stratify* Black (n = 92) |
Hispanic (n = 103) |
|
| ApoC-III | ||||||
| -482C/T (rs2854117) | 4 | - | 1 | 1 | - | - |
| -455T/C (rs2854116) | - | 3 | 2 | 3 | - | - |
| intron 1 (466)G/C (rs2070669) | - | - | - | - | - | - |
| Gly34Gly C/T (rs4520) | - | - | - | - | - | - |
| exon 4 SstI 4348(5) C/G (rs5128) | - | - | - | - | - | - |
| ApoE | ||||||
| Arg112Cys T/C (rs429358) | - | - | 1 | - | - | - |
| Arg158Cys T/C (rs7412) | 3 | 1 | - | 2 | - | - |
| EL | ||||||
| rs12970066, | 5 | - | - | 4 | 1 | - |
| Asn396Ser, | 4 | - | - | 1 | 1 | - |
| rs3829632 (-1309A/G) | - | - | - | - | - | - |
| HL | ||||||
| rs2070895 | 3 | 1 | - | 2 | - | - |
| rs12595191 | - | - | - | - | - | - |
| rs690, | 4 | 2 | - | 1 | - | - |
| rs6084 | 2 | - | 1 | - | 1 | - |
| Race/ethnicity | 1 | NA | NA | NA | NA | NA |
" * " indicates the approach to handling the race/ethnicity covariate;
"NA" indicates that the predictor was not included in the analysis;
and "-" indicates that the predictor was not selected in the final MARS model.