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. 2009 Jan;22(1):127–145. doi: 10.1128/CMR.00026-08

TABLE 6.

Case definition for human trichinellosis according to the European Center for Disease Controla

Criterion group Prerequisites and case classificationb
Clinical At least three of the following six: fever, muscle soreness and pain, gastrointestinal symptoms, facial edema, eosinophilia, and subconjunctival, subungual, and retinal hemorrhages
Laboratory At least one of the following two laboratory tests: demonstration of Trichinella larvae in tissue obtained by muscle biopsy and demonstration of Trichinella-specific antibody response by indirect immunofluorescence, ELISA, or Western blot (i.e., seroconversion)
Epidemiological At least one of the following three: consumption of laboratory-confirmed parasitized meat, consumption of potentially parasitized products from a laboratory-confirmed infected animal, epidemiological link to a laboratory-confirmed human case by exposure to the same common source
a

Modified from reference 29 with permission of the publisher.

b

Case classification is as follows: possible case, not applicable; probable case, any person meeting the clinical criteria and with an epidemiological link; confirmed case, any person meeting the laboratory criteria and with clinical criteria within the past 2 months (to be reported to the European Union level).