TABLE 3.
Proteins with increased levels in A. fumigatus cultures grown in AMM after supplementation with 10 mM l-tyrosine
| Spot no.a | Protein namec | Sequence coverage (%) | Mascot scoreb | Protein molecular mass (kDa) | Accession no. |
|---|---|---|---|---|---|
| 1 | NADH-quinone oxidoreductace Pst2 | 64 | 1,117 | 21.8 | gi:66847664 |
| 2 | Nucleoside diphosphate kinase | 68.6 | 87 | 16.9 | gi:70984978 |
| 3 | Peptidyl-prolyl cis-trans isomerase/cyclophilin | 42.9 | 73.4 | 17.7 | gi:66852503 |
| 4 | Malate dehydrogenase, NAD dependent | 61.8 | 165 | 35.9 | gi:70986899 |
| 5 | Glyceraldehyde 3-phosphate dehydrogenase | 39.1 | 111 | 36.4 | gi:70985278 |
| 6 | Aspartate transaminase | 58.2 | 187 | 51.2 | gi:66852936 |
| 7 | Aldehyde dehydrogenase | 57.4 | 165 | 54.7 | gi:70982606 |
| 8 | Homogentisate 1,2-dioxygenase | 43.7 | 126 | 50.2 | gi:70989409 |
| 9 | Fumarylacetoacetate hydrolase | 41.3 | 132 | 46.8 | gi:70989411 |
| 10 | Alcohol dehydrogenase | 70 | 165 | 37.9 | gi:70982604 |
Spot number according to Fig. 1B.
Mascot score represents the probability that the observed match is a random event. Only protein scores with P values of <0.05 were considered significant.
Proteins in bold are involved in tyrosine metabolism via HGA.