TABLE 1.
Agent | MICa for strain:
|
||
---|---|---|---|
H37Rv | H37Rv bacA::hyg | H37Rv bacA::hyg- pKLMt5 | |
Bleomycin | 9-18 ng ml−1 | 16-32× | 4× |
SDS | 0.03%, wt/vol | 1× | 1× |
DOC | 0.01%, wt/vol | 1× | 1× |
ZnSO4 | 1.5 mg ml−1 | 1× | 1× |
Bleomycin in Fe-depleted GAST | 9-18 ng ml−1 | 4× | 2× |
Values are expressed as the ratio of the MIC obtained for the mutant to that obtained for the parental strain, H37Rv. Values were determined from three independent experiments, each performed in duplicate.