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MICs of chelating agents
| Agent | MICa for strain:
|
||
|---|---|---|---|
| H37Rv | H37Rv bacA::hyg | H37Rv bacA::hyg- pKLMt5 | |
| EDTA | 100 μM | 1× | 1× |
| Dypiridyl | 250 mM | 0.5× | 1× |
| Deferoxamine | 2-4 mM | 0.25-0.5× | 0.5× |
| CuSO4 | 10 mg ml−1 | 1× | 1× |
Values for the mutants are expressed as the ratio of the MIC obtained for the mutant to that obtained for the parental strain, H37Rv. Values were determined from three independent experiments, each performed in duplicate.
