FIG. 6.

Comparison of the genomic regions upstream of genes vtaA19, vtaA10, and vtaA12. Boxes represent genes. Abbreviations: CHP, conserved hypothetical protein; TRP, divalent cation transporter; menC, gene encoding O-succinylbenzoate synthase. Light gray shaded areas correspond to high-homology regions (identities of 90% or more) shared between the different genes or intergenic spaces whose length in bp are indicated by values below or above the brackets. With the exception of 71 nucleotides, the entire menC gene has been deleted in HP-1302, and the CHP gene in this strain is a pseudogene with numerous frameshifts. The signal peptide region is magnified to show the exact extent of the deletion in vtaA19. The arrow indicates the most probable cleavage site of the signal peptide.