TABLE 3.
Neutralization titers of 11 subtype B and 10 subtype C plasmas against HIV-2, HIV-1, and HIV-2/HIV-1 V3 chimeras
| Plasma | Subtype | Reciprocal IC50a
|
||||
|---|---|---|---|---|---|---|
| HIV-2KR.X4 | HIV-2KR.X7 | HIV-2KR.X7 Ccon V3 | HIV-2KR.X7 YU2 V3 | HIV-1YU-2 | ||
| DIGA 3757 | B | <20 | <20 | 285 | 20,777 | 158 |
| 1705 | B | <20 | <20 | 833 | 6,849 | <20 |
| 1682 | B | <20 | <20 | 2,453 | 6,098 | 33 |
| YOAL 0522 | B | <20 | <20 | 1,306 | 3,804 | <20 |
| MIGE 1132 | B | <20 | <20 | 794 | 2,449 | <20 |
| RUTH 1145 | B | <20 | <20 | 740 | 873 | <20 |
| SMST 1012 | B | <20 | <20 | 3,102 | 9,259 | 47 |
| WATI 0885 | B | <20 | <20 | 45 | 331 | <20 |
| LENA 1029 | B | <20 | <20 | 674 | 3,189 | <20 |
| BELI 1233 | B | <20 | <20 | 3,529 | 6,080 | <20 |
| HIDO 1099 | B | <20 | <20 | 628 | 305 | <20 |
| BB10 | C | <20 | <20 | 4,713 | 96 | <20 |
| BB22 | C | <20 | <20 | 8,197 | 3,578 | 26 |
| BB25 | C | <20 | <20 | 4,847 | 3,347 | 21 |
| BB52 | C | <20 | <20 | 14,096 | 722 | 27 |
| BB70 | C | <20 | <20 | 21,618 | 15,104 | 147 |
| BB72 | C | <20 | <20 | 2,530 | 1,085 | <20 |
| BB83 | C | <20 | <20 | 42,369 | 936 | 20 |
| BB105 | C | <20 | <20 | 7,987 | 13,736 | <20 |
| BB106 | C | <20 | <20 | 13,062 | 198 | 37 |
| BB107 | C | <20 | <20 | 8,780 | 2,358 | 198 |
| HIV-1 negative | <20 | <20 | <20 | <20 | <20 | |
a
Neutralization titers are expressed as the reciprocal IC50 plasma dilution of a representative experiment. Experiments were repeated at least three times.