TABLE 3.
Identification of the phenotype of HCV NS3-positive cells by real-time PCR and double immunostaining in autopsy brain tissue samples from 12 HCV-infected patientsa
| Patient no. | Dominant cell-identifying transcript | % Positive by immunostaining for:
|
|||
|---|---|---|---|---|---|
| CD68 | GFAP | NeuN | CNPase | ||
| 1 | CD68+ | 86 | 18 | 0 | 0 |
| 2 | CD68+ | 95 | 12 | 0 | 0 |
| 3 | CD68+ | 90 | 9 | 0 | 0 |
| 4 | CD68+ | 83 | 6 | 0 | 0 |
| 5 | CD68+ | 80 | 29 | 0 | 0 |
| 6 | CD68+ | 95 | 7 | 0 | 0 |
| 7 | CD68+ | 92 | 5 | 0 | 0 |
| 8 | CD68+ | 90 | 8 | 0 | 0 |
| 9 | CD68+ | 90 | 11 | 0 | 0 |
| 10 | CD68+ | 86 | 4 | 0 | 0 |
| 11 | CD68+ | 85 | 12 | 0 | 0 |
| 12 | CD68+ | 93 | 8 | 0 | 0 |
All five HCV-negative control patients, two of whom were HIV positive, were negative for NS3 staining.