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Dose–response curve showing that activation of central NPY receptors inhibits baseline startle. Each animal received an infusion of vehicle, 1, 3, or 10 μg of NPY on each of four days in a counterbalanced manner 60 min before baseline startle testing. NPY had a dose-dependent effect on decreasing baseline startle [overall effect between treatments (F (3,61) = 4.09, p < 0.05); values shown are the average of all trials; error bars indicate ±SEM; *p < 0.05 compared with vehicle].
