Figure 1.—
Effects of 5-HT on egg laying in animals expressing combinations of 5-HT receptors. Egg laying was assayed on NGM agar plates in the presence or absence of 5-HT or bacteria (E. coli OP50), as described in materials and methods. At least three trials with 15 animals/trial were performed for each strain. Data presented as mean ±SE and analyzed by two-tailed Student's t-test. *P < 0.001, significantly different from wild-type animals examined under identical conditions. ○, N2; ▪, ser-4;mod-1; •, ser-7 ser-1; and ▴, ser-4;mod-1;ser-7 ser-1.