TABLE 3.

Comparisons of estimates of θ (per kb) for the data of Venter et al. (2001) and for a set of 1000 simulated data sets

Data	a	b	c
Celera data	1.67	1.13	1.21
Simulated data	1.68 (0.9)	1.36 (0.6)	1.39 (0.6)

Columns indicate estimates resulting from (a) the method of Hellmann et al. (2008), (b) the method presented in this article, and (c) the extension of our approach to perform calculations conditional on observed rather than expected coverage. We show the mean estimate for the data of Venter et al. (2001) and the mean (and RMSE) for the simulated data.