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. Author manuscript; available in PMC: 2009 Jan 12.
Published in final edited form as: J Am Chem Soc. 2008 Jun 21;130(28):9006–9012. doi: 10.1021/ja800086u

Figure 3.

Figure 3

Comparison of gene silencing efficiencies between proton-sponge coated QDs and commercial transfection reagents by western blotting. The level of cyclophilin B protein expression was reduced to 1.81%±1.47% by QDs, to 13.45%±9.48% by Lipofectamine, to 30.58%±6.90% by TransIT, and to 51.00%±11.46% by JetPEI (corresponding to efficiency improvements of 7.4, 16.9, and 28.2 fold, respectively). The quantitative values were obtained from the western blot (inset). On the average, the proton-sponge coated QDs are 18 times as efficient as the three transfection agents commonly used.