Table II. Inhibition of EAU induction in arrβgal × βgalTCR double Tg mice.
arrβgal | arrβgal × βgalTCR | ||||
---|---|---|---|---|---|
Immunization | incidence | severity | incidence | severity | P valuea |
βgal + CFA | 0/8 | 0 | 0/15 | 0 | |
βgal + CFA + PTx | 12/36 | 0.5, 0.5, 0.5, 1, 1, 1, 2, 2, 2.5, 3, 3.5, 4 | 0/12 | 0 | 0.023 |
Fisher’s exact test: 2-tailed; arrβgal vs. arrβgal × βgalTCR