Skip to main content
. 2009 Jan 22;4(1):e4250. doi: 10.1371/journal.pone.0004250

Figure 2. Effect of mitoquinone (mQN) and mitoquinol (mQL) compared to control compounds on H2O2 production by isolated BAE mitochondria fueled by different substrates.

Figure 2

Mitochondria were incubated in respiratory buffer under state 4 conditions fueled by pyruvate (pyr), glutamate (glut)+malate (mal), or succinate (succ) as indicated above the individual graphs. Added compounds (1.0 µM), vehicle, or FCCP (2.5 µM) were present as indicated on the X-axis. Data represent mean±SE, * p<0.01 compared to vehicle by ANOVA. n = 6 mitochondrial preparations for all data points. Each individual value represents the mean of two replicate wells.