Skip to main content
. Author manuscript; available in PMC: 2009 Jan 12.
Published in final edited form as: J Mol Biol. 2006 Mar 30;358(4):1179–1190. doi: 10.1016/j.jmb.2006.02.075

Figure 2.

Figure 2

a) and b) Colored secondary structure diagram representation of the L-21 T. thermophila group I intron. Colors represent regions of molecule exhibiting similar time-progress curves during folding in the Mg2+ and Na+ mediated folding, as determined by k-means clustering of site-specific progress curves. Boxes indicate sites of protection that were monitored on the molecule, these are also listed in the Supplementary Material. c) and d) Best fitting kinetic model predictions (lines) to time-progress curves for the Mg2+ and Na+ mediated folding, respectively. Fractional saturation calculated based on hydroxyl radical footprinting protection data is plotted with × symbols. Colors correspond to the different regions of the molecule as defined in a) and b).