Table 2.

Control HDL metabolism in apo A-II knockout mice and controls

Mouse	n	HDL-C, mg/dl	HDL CE FCR, pools/h	HDL CE TR, units	Apo A-I, mg/dl	Apo A-I FCR, pools/h	Apo A-I TR, units
+/+	5	61  ± 9	0.19  ± 0.01	8.6  ± 0.9	184  ± 16	0.10  ± 0.01	18.5  ± 3.0
−/−	6	22  ± 5***	0.26  ± 0.03***	4.3  ± 0.7***	74  ± 13***	0.14  ± 0.02**	10.4  ± 1.6***

HDL isolated from controls was double labeled with ¹²⁵I and ³H and injected into controls and apo A-II knockout mice; ∗∗, P < 0.01 as compared to controls; and ∗∗∗, P < 0.001 as compared to controls.