Table 3.

A-II knockout HDL metabolism in apo A-II knockout mice and controls

Mouse	n	HDL-C, mg/dl	HDL CE FCR, pools/h	HDL CE TR, units	Apo A-I, mg/dl	Apo A-I FCR, pools/h	Apo A-I TR, units
+/+	6	52  ± 13	0.21  ± 0.01	8.3  ± 2.2	156  ± 22	0.10  ± 0.01	15.9  ± 2.4
−/−	4	15  ± 3***	0.32  ± 0.02***	3.7  ± 0.8**	62  ± 15***	0.18  ± 0.01***	11.0  ± 2.7*

HDL isolated from apo A-II knockout mice was double labeled with ¹²⁵I and ³H and injected into controls and apo A-II knockout mice: ∗, P < 0.05 as compared to controls; ∗∗, P < 0.01 as compared to controls; and ∗∗∗, P < 0.001 as compared to controls.