TABLE 1.

Organ weights (wet mass and normalized mass) for male and female rats on the different dietary regimens

Organ		Male			Female
		Wet mass (mg)	Normalized mass (mg)	Modulation	Wet mass (mg)	Normalized mass (mg)	Modulation
Adrenal (L)
	Control	27.92 ± 1.3	27.92		37.5 ± 1.2	37.5
	20% CR	29.42 ± 0.8	36.78 ± 0.6	↑a	38.28 ± 2.8	50.15 ± 0.9	↑b
	40% CR	25.14 ± 0.6	38.97 ± 0.3	↑a	32.87 ± 1.6	52.2 ± 2.3	↑b
	IF	29.12 ± 1.1	45.13 ± 0.3	↑b	33.12 ± 1.4	40.0 ± 1.8	↑a
	HFG	33.85 ± 0.5	31.14 ± 0.2	↑a	37.0 ± 2.3	40.33 ± 2.1	↑a
Kidney (L)
	Control	1703.53 ± 84.5	1703.53		1035.66 ± 42	1035.66
	20% CR	1517.62 ± 93.9	1897 ± 49	↑a	944.25 ± 33	1236.9 ± 30	↑a
	40% CR	1260.62 ± 40.5	1953.9 ± 42	↑b	747.25 ± 28	1188.1 ± 28	↑a
	IF	1495.5 ± 81.3	1869.4 ± 37	↑a	981.12 ± 18	1187.1 ± 18	↑a
	HFG	1807.37 ± 79	1671.4 ± 28	↑a	968.75 ± 22	1055.9 ± 16	↑
Gonad (L)
	Control	2125.73 ± 88	2125.73		75.4 ± 2.3	75.4
	20% CR	2176.62 ± 76	2720.7 ± 54	↑b	61.75 ± 4.5	80.8 ± 3.1	↑a
	40% CR	2163.75 ± 65	3353.8 ± 48	↑c	63.12 ± 4.3	100.3 ± 2.9	↑b
	IF	2186.12 ± 98	2732.7 ± 71	↑a	60.87 ± 5.8	73.6 ± 3.5	↓
	HFG	2116.5 ± 74	1957.7 ± 43	↓a	65.5 ± 3.6	71.3 ± 2.9	↑a
Heart
	Control	1911.76 ± 58	1911.76		1142.66 ± 32	1142.66
	20% CR	1710.37 ± 66	2137.9 ± 25	↑a	1089.62 ± 28	1427.4 ± 18	↑a
	40% CR	1528.62 ± 94	2369.4 ± 27	↑b	970.5 ± 15	1543.1 ± 13	↑a
	IF	1637.25 ± 75	2046.3 ± 32	↑a	1067.87 ± 22	1292.1 ± 21	↑a
	HFG	1873.25 ± 43	1732.8 ± 28	↓b	1063 ± 36	1158.7 ± 33	↑
Spleen
	Control	885.53 ± 24	885.53		700.53 ± 18	700.53
	20% CR	841.12 ± 28	1051.4 ± 23	↑b	630 ± 22	825.3 ± 15	↑b
	40% CR	633.5 ± 33	981.9 ± 19	↑a	482.12 ± 37	766.5 ± 31	↑a
	IF	795.87 ± 43	994.8 ± 37	↑a	609.12 ± 28	968.5 ± 22	↑b
	HFG	946.5 ± 55	875.5 ± 29	↓	717.12 ± 26	781.6 ± 15	↑a

Arrows pointing upward denote an increase, whereas arrows pointing downward denote a decrease. Values are mean ± sem (n = 8–15 rats/group).

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.