TABLE 5.
Monoamine neurotransmitter and metabolite levels in the cerebellum of male and female rats with different dietary energy intakes
| Neurotransmitter | Male mean ± sem (pg/mg) |
Female mean ± sem (pg/mg) |
|
|---|---|---|---|
| NE | |||
| Control | 238.2 (±15.8) | 218.1 (±12.5) | |
| 20% CR | 231.7 (±18.4) | 208.5 (±19.8) | |
| 40% CR | 249.7 (±21.8) | 197.1 (±14.6)↓a | |
| IF | 256.3 (±19.4) | 242.4 (±25.6) | |
| HFG | 284.4 (±21.7) | 255.0 (±22.7) | |
| DOPAC | |||
| Control | 165.2 (±18.2) | 188.6 (±32.5) | |
| 20% CR | 186.0 (±28.9) | 199.8 (±24.5) | |
| 40% CR | 190.6 (±6.9) | 192.9 (±13.7) | |
| IF | 231.0(±13.2)↑a | 281.9 (±15.8)↑a | |
| HFG | 217.5 (±12.7)↑a | 242.0 (±6.8) | |
| 5HIAA | |||
| Control | 17.3 (±3.4) | 20.7 (±2.6) | |
| 20% CR | 11.7 (±2.9) | 17.3 (±4.1) | |
| 40% CR | 19.0 (±2.1) | 27.1 (±5.2) | |
| IF | 11.3 (±3.6)↓a | 10.7 (±2.4)↓a | |
| HFG | 13.9 (±2.2) | 18.0 (±3.6) | |
| 5HT | |||
| Control | 35.7 (±2.8) | 35.8 (±2.0) | |
| 20% CR | 35.1 (±4.6) | 35.9 (±2.7) | |
| 40% CR | 32.0 (±3.4) | 38.8 (±2.9) | |
| IF | 35.2 (±2.1) | 38.3 (±3.7) | |
| HFG | 32.9 (±1.3) | 37.5 (±2.6) | |
Arrows pointing upward denote an increase, whereas arrows pointing downward denote a decrease. Values are mean ± sem (n = 8–15 rats/group).
a
P < 0.05.