TABLE 6.
Monoamine neurotransmitter and metabolite levels in the striatum of male and female rats with different dietary energy intakes
| Neurotransmitter | Male mean ± sem (pg/mg) |
Female mean ± sem (pg/mg) |
|
|---|---|---|---|
| NE | |||
| Control | 205.7 (±42.1) | 253.5 (±66.2) | |
| 20% CR | 220.5 (±10.7) | 242.5 (±29.8) | |
| 40% CR | 231.1 (±57.1)↑a | 242.1 (±52.9) | |
| IF | 157.6 (±25.2) | 177.2 (±46.8) | |
| HFG | 162.4 (±23.6) | 164.5 (±20.1) | |
| DOPAC | |||
| Control | 1657.3 (±98.9) | 1462.9 (±68.7) | |
| 20% CR | 1493.2 (±102.5) | 1595.1 (±49.0) | |
| 40% CR | 1615.4 (±118.8) | 1586.3 (±88.5) | |
| IF | 1635.2 (±82.0) | 1557.8 (±64.0) | |
| HFG | 1456.2 (±52.7) | 1472.2 (±86.7) | |
| DA | |||
| Control | 3771.1 (±196.9) | 3648.3 (±140.4) | |
| 20% CR | 3613.3 (±143.1) | 3897.7 (±114.9) | |
| 40% CR | 3968.1 (±242.0) | 3891.1 (±182.6) | |
| IF | 4135.6 (±86.7) | 3917.7 (±133.9) | |
| HFG | 4035.7 (±174.6) | 4060.6 (±164.6) | |
| 5HIAA | |||
| Control | 595.8 (±87.1) | 574.4 (±33.7) | |
| 20% CR | 438.1 (±33.8) | 557.4 (±26.2) | |
| 40% CR | 512.9 (±43.0) | 667.8 (±44.3) | |
| IF | 469.7 (±24.9) | 575.9 (±69.3) | |
| HFG | 487.7 (±19.2) | 559.2 (±44.3) | |
| 5HT | |||
| Control | 444.0 (±82.6) | 347.7 (±83.7) | |
| 20% CR | 307.7 (±61.7) | 345.1 (±81.8) | |
| 40% CR | 325.7 (±69.6) | 423.8 (±75.7) | |
| IF | 358.2 (±66.8) | 427.6 (±69.9) | |
| HFG | 359.2 (±64.0) | 365.1 (±49.8) | |
| HVA | |||
| Control | 554.2 (±88.1) | 629.9 (±49.5) | |
| 20% CR | 557.9 (±30.9) | 609.9 (±33.5) | |
| 40% CR | 609.0 (±65.2)↑a | 660.9 (±28.9) | |
| IF | 572.3 (±38.4) | 569.8 (±39.8) | |
| HFG | 467.9 (±17.7) | 638.2 (±65.2) | |
Arrows pointing upward denote an increase, whereas arrows pointing downward denote a decrease. Values are mean ± sem (n = 8–15 rats/group).
a
P < 0.05.