Table 3.
Adjusted HR for incident microalbuminuria associated with each 10-cm greater waist circumference, by covariate subgroup
| Group | No. of Events/No. at Risk | Adjusted HR (95% CI)a | Pb |
|---|---|---|---|
| All patients | 93/1105 | 1.34 (1.07 to 1.68) | |
| Age (yr) | |||
| <30 | 23/276 | 1.31 (0.84 to 2.04) | 0.890 |
| 30 to 40 | 36/514 | 1.30 (0.93 to 1.81) | |
| >40 | 34/222 | 1.44 (1.03 to 1.99) | |
| Gender | |||
| female | 30/486 | 1.65 (1.12 to 2.42) | 0.209 |
| male | 63/526 | 1.23 (0.94 to 1.62) | |
| Race | |||
| white | 88/983 | 1.35 (1.08 to 1.70) | 0.867 |
| nonwhite | 5/29 | 0.82 (0.20 to 3.45) | |
| DCCT treatment group | |||
| intensive | 26/554 | 1.40 (1.03 to 1.89) | 0.697 |
| conventional | 67/458 | 1.29 (0.95 to 1.75) | |
| HbA1c (%) | |||
| <7 | 4/240 | 1.71 (0.81 to 3.63) | 0.470 |
| 7 to 9 | 24/527 | 1.45 (1.06 to 1.99) | |
| >9 | 65/245 | 1.18 (0.88 to 1.58) | |
| AER (mg/24 h) | |||
| <10 | 31/598 | 1.23 (0.83 to 1.80) | 0.805 |
| 10 to 20 | 35/342 | 1.29 (0.93 to 1.77) | |
| 20 to 30 | 27/72 | 1.45 (0.99 to 2.10) |
a
Discrete proportional hazards model includes waist circumference (scaled to 10 cm), age, gender, race, duration of diabetes, DCCT treatment group, smoking status, HbA1c, and AER, each measured at DCCT closeout.
b
Tests hypothesis that HR differs among subgroups of covariate.