Prevalence and Incidence of Albuminuria
Albuminuria defined as albumin excretion rate ≥208 μg/min, equivalent to 300 mg/24 h. A, Prevalence of clinical albuminuria at the end of the Diabetes Control and Complications Trial (DCCT) and during the Epidemiology of Diabetes Interventions and Complications (EDIC) study. The differences between the treatment groups are significant at each time point after DCCT close-out (P<.01). B, Cumulative incidence of new cases in the EDIC study for those participants in the intensive- and conventional-treatment groups with either normoalburninuria or microalbuminuria at the end of the DCCT. The difference in cumulative incidences is significant by the tog-rank-test. (P<.001).