Table 2.
Patients With Kidney Outcomes Through Year 8 in the EDIC Study*
| Outcome | Original DCCT Treatment Group, No. (%) |
P Value† |
||
|---|---|---|---|---|
| Total (N=1349) |
Intensive (n=676) |
Conventional (n=673) |
||
| Doubling of serum creatinine level | 27(2.0) | 10(1.5) | 17(2.5) | .17 |
| since DCCT baseline | ||||
| Serum creatinine >2 mg/dL | 15(1.1) | 4(0.6) | 11(1.6) | .21 |
| Dialysis or kidney transplant | 4(0.3) | 3(0,4) | 1(0.1) | 13 |
| Serum creatinine >2 mg/dL | 24(1.8) | 5(O.7) | 19(2.8) | .004 |
| Dialysis or kidney transdant | 11(0.8) | 4(0.6) | 7(1.O) | .14 |
| Dialysis or kidney transplant | 11(0.8) | 4(0.6) | 7(1.O) | .36 |
| Dialysis | 9(0.7) | 4(0.6) | 5(0.7) | .49 |
| Kidney transplant | 7(0.5) | 2(0.3) | 5(0.7) | .56 |
Abbreviations: DCCT, Diabetes Control and Complications Trial; EDIC, Epidemiology of Diabetes Interventions and Complications.
SI conversion factor: To convert mg/dL to μmol/L for serum creatinine, multiply mg/dL values by 88.4.
*
Indudes 1 patient with serum creatinine level ≥2 mg/dL during the DCCT.
†
From 2 χ2 or Fisher exact test.