Table 2.

Descriptive statistics for measurements of P2X₇ pore activity in clinical samples from asthma patients. Whole blood samples were obtained locally as a part of the Natural Cold in Asthma study or through an ongoing multi-center clinical trial (Macrolides In Asthma; ACRN-MIA) via the Asthma Clinical Research Network. Data represent the BzATP-induced fold-stimulation of YO-PRO-1 uptake fluorescence. Seventeen of the thirty-one Natural Cold subjects had samples obtained both during the acute and baseline phases of a naturally occurring upper respiratory viral infection, in which case the mean value was compiled for the group descriptors. The remainder of the Natural Cold, and all of the ACRN-MIA, patients had samples measured from one visit only. Samples greater than one day old were excluded from analysis in the Natural Cold protocol due to the absence of dead cell exclusion. CD14-PE^pos/PI^pos cells were uniformly excluded in the ACRN-MIA study and samples up to four days old were processed with the data presented. ACRN-MIA subjects with samples older than 4 days due to shipping delays were redrawn at another visit if possible.

	Natural Cold Data (Recalled Settings) N = 31	ACRN-MIA Data (Bead-adjusted Settings) N = 99
Minimum	13.8	2.3
1st Quartile	359	274
Median	669.5	598
3rd Quartile	992	893.5
Maximum	1676	1666