Table 2.
Variable | Quartile of Weight Gain | |||
---|---|---|---|---|
First | Second | Third | Fourth | |
Hemoglobin A1c , % | 9.5 (1.6) [+11]† |
9.2 (1.5) [+7.0]† |
9.1 (1.5) [+2.2] |
8.9 (1.3)‡ [0] |
Body mass index, kg/m2 | 24 (2.6) [−4.0]† |
24 (2.5) [+4.4]† |
25 (2.6)§∥ [+4.2]† |
27 (3.3)]§∥¶ [+13]† |
Systolic BP, mm Hg | 113 (15) [−2.6]# |
115 (11) [0] |
116 (13) [0] |
119 (13)‡# [+2.6]** |
Diastolic BP, mm Hg | 74 (11) [0] |
73 (10) [0] |
75 (8) [+2.7]** |
76 (9) [+4.1]** |
Insulin dose, u/kg per day | 0.60 (0.19) | 0.61 (0.15) | 0.62 (0.15) | 0.66 (0.17)§ |
Waist-to-hip ratio | 0.82 (0.07) | 0.81 (0.08) | 0.82 (0.08) | 0.84 (0.1) |
Severe hypoglycemia, episodes per subject |
1 (2) | 2 (5) | 1 (2) | 1 (2) |
Results are expressed as mean (SD). Results in brackets are percent change from baseline. Body mass index is a measure of weight in kilograms divided by the square of height in meters. BP indicates blood pressure.
P<.001 compared with baseline.
P<.01 vs first quartile.
P<.001 vs first quartile.
P<.001 vs second quartile.
P<.001 vs third quartile.
P<.01 vs second quartile.
P <.05 compared with baseline.