Table 4.

Follow-up Characteristics of Quartiles of Weight Gain of Intensively Treated Group^a

Variable	Quartile of Weight Gain
	First	Second	Third	Fourth
Hemoglobin A1c, %	7.3 (1.3) [−16.1]b	7.2 (1.0) [−15.3]b	7.1 (1.0) [−20.2]b	7.3 (0.9) [−20.7]b
Body mass index, kg/m2	24 (2.3) [0]	25 (2.5)c [+8.7]b	27 (2.9)cd [+17]b	31 (4.7)cde [+29]b
Systolic BP, mm Hg	113 (11) [−0.9]	117 (11) [+2.6]f	115 (15) [+0.9]	120 (12)cgh [+5.3]b
Diastolic BP, mm Hg	73 (8) [+1.4]	74 (9) [+2.8]	74 (11) [+1.4]	77 (8)cih [+5.5]b
Insulin dose, u/kg per day	0.61 (0.19)	0.64 (0.17)	0.69 (0.22)c	0.74 (0.22)cd
Severe hypoglycemia, episodes per subject	4 (8)	5 (8)	5 (7)	5 (8)j
Waist-to-hip ratio	0.81 (0.09)	0.82 (0.09)	0.82 (0.09)	0.83 (0.12)k

^aResults are expressed as mean (SD). Results in brackets are percent change from baseline.

^bP<.001 compared with baseline.

^cP<.001 vs first quartile.

^dP<.001 vs second quartile.

^eP<.001 vs third quartile.

^fP<.05 compared with baseline.

^gP<.05 vs fourth quartile.

^hP<.01 vs third quartile.

ⁱP<.01 vs second quartile.

^jP<.05 vs first quartile.

^kP<.01 vs first quartile.