Table 5.
Lipid Levels at Follow-up by Quartile of Weight Gain in the Intensively Treated Group*
| Variable | Quartile of Weight Gain | |||
|---|---|---|---|---|
| First | Second | Third | Fourth | |
| Triglyceride, mmol/L [mg/dL] | 0.79 (0.38) [70 (34)] [−14.4]† |
0.82 (0.52) [73 (46)] [−4.8] |
0.91 (0.59) [81 (52)] [6] |
0.99 (0.45) [88 (40)]‡§∥ [7.8] |
| Total cholesterol, mmol/L [mg/dL] | 4.50 (0.80) [174 (31)] [−5.9]† |
4.53 (0.72) [175 (28)] [1.8] |
4.63 (0.78) [179 (30)] [1.1] |
4.86 (0.72) [188 (28)]द [3.8]# |
| LDL, mmol/L [mg/dL] | 2.74 (0.70) [106 (27)] [−8.7]† |
2.79 (0.65) [108 (25)] [1.8] |
2.92 (0.72) [113 (28)] [0.7] |
3.15 (0.65) [122 (25)]‡§∥ [6.8]† |
| HDL, mmol/L [mg/dL] | 1.40 (0.34) [54 (13)] [2.2] |
1.34 (0.36) [52 (14)] [1.5] |
1.29 (0.34) [50 (14)] [−2.3] |
1.27 (0.31) [49.1 (12)]‡ [−3.8]† |
| Apo B, g/L | 0.78 (0.18) | 0.80 (0.18) | 0.84 (0.27) | 0.89 (0.17)‡§∥ |
| LDL Rf | 0.31 (0.02) | 0.31 (0.03) | 0.31 (0.03) | 0.30 (0.03)** |
| Apo A-I, g/L | 1.42 (0.22) | 1.39 (0.23) | 1.36 (0.22) | 1.36 (0.23)†† |
| Lp(a), g/L | 1.3 | 8.6 | 1.0 | 1.3 |
*
Results are expressed as mean (SD) except Lp(a), which is reported as median. Results listed last in brackets are percent change from baseline. LDL indicates low-density lipoprotein; HDL, high-density lipoprotein; apo B, apolipoprotein B; Rf, relative flotation; apo A-I, apolipoprotein A-I; and Lp(a), lipoprotein(a).
†
P<.001 compared with baseline.
‡
P<.001 vs first quartile.
§
P<.001 vs second quartile.
∥
P<.001 vs third quartile.
¶
P<.05 vs third quartile.
#
P<.01 compared with baseline.
**
P<.01 vs first quartile.
††
P<.05 vs first quartile.