In vitro binding of proteins to
fragments of the ech-42 promoter. (A)
Schematic representation of the method used to prepare the DNA
fragments for EMSA. PCR was performed with combinations of primers 221,
E1, E2, and E3 as described. The final 221 plus E3 amplification
product was sequenced and digested with SalI to obtain
the two fragments used for EMSA (S1 and S2). (B) EMSA, using
protein extracts of T. harzianum and two fragments of
the ech-42 promoter region. Lanes: 1, free DNA; 2, DNA
plus extract from a3; 3, DNA plus extract from a1; 4, DNA plus protein
extracts from the mycelium of a T. harzianum–T.
harzianum interaction; and 5, DNA plus protein extracts from
mycelium of B. cinerea during a2.