Table 4.

P-values of the 18 pathways that include PRKAR2B gene by the six methods (with p-value or FDR < 0.05 in bold).

						GSEA
Gene set	SAM-GS	Global	ANCOVA global	Tian	Tomfohr	P	FDR
INS	0.002	0.031	0.022	0.004	1.000	0.038	0.664
amiPathway	0.042	0.054	0.032	0.002	1.000	0.117	0.777
cskPathway	0.042	0.054	0.032	0.002	1.000	0.117	0.743
mprPathway	0.128	0.180	0.161	0.148	0.984	0.138	0.756
gpcrPathway	0.217	0.202	0.169	0.386	1.000	0.063	0.661
no1Pathway	0.355	0.270	0.248	0.528	1.000	0.642	0.931
nfatPathway	0.386	0.335	0.347	0.396	1.000	0.898	0.948
vipPathway	0.403	0.350	0.328	0.462	1.000	0.394	0.970
nos1Pathway	0.413	0.454	0.431	0.926	1.000	0.153	0.744
mcalpainPathway	0.621	0.629	0.601	0.190	1.000	0.625	1.000
pparaPathway	0.665	0.674	0.668	0.130	1.000	0.549	0.934
shh_lisa	0.671	0.689	0.661	0.294	1.000	0.496	0.963
ck1Pathway	0.704	0.758	0.762	0.174	1.000	0.123	0.793
crebPathway	0.732	0.798	0.806	0.708	1.000	0.119	0.756
chrebpPathway	0.745	0.809	0.804	0.232	1.000	0.155	0.753
CR_PROTEIN_MOD	0.760	0.805	0.788	0.852	1.000	0.608	0.920
badPathway	0.830	0.876	0.854	0.480	1.000	0.747	0.948
gata3Pathway	0.921	0.883	0.880	0.522	1.000	0.555	0.933