Supplementary Table 1.

Estimated parameters in Table 2 between cancer and normal cells under different stresses.

	Heat shock		Oxidative Stress		ER stress
	Cancer	Normal	Cancer	Normal	Cancer	Normal
α1,1	1.044	0.7268	0.9574	0.9616	0.9177	1.074
α1,3	−0.1026	0.1134	0.006334	0.1298	−0.04867	0.00081
α1,6	0.05995	0.00317	−0.004416	0.03642	−0.007575	0.1465
α1,7	0.01031	0.6302	0.04509	0.1503	−0.02275	−0.2139
α2,1	−0.1564	0.009837	−0.07192	0.008701	0.5371	−0.03559
α2,2	0.8959	0.9048	0.8932	0.957	1.07	0.8758
α2,10	−0.1103	−0.003157	0.102	−0.03569	−0.02597	−0.3406
α3,1	1.745	−0.3639	−0.7279	0.07657	0.2551	0.09949
α3,2	0.429	2.362	0.8698	−0.2835	0.1324	−0.1144
α3,3	0.8536	0.6808	0.2286	0.9705	0.8011	0.9916
α3,5	0.545	−1.227	0.6009	0.01383	0.006959	0.2713
α3,6	0.3013	−0.1417	0.3345	0.1314	−0.1614	−0.02891
α3,13	0.775	1.028	−0.1643	0.2014	0.1074	−0.0713
α3,15	0.4395	0.3443	−0.639	−0.1043	−0.1206	0.1221
α3,16	0.4395	0.3443	−0.06912	0.1243	0.0601	0.08655
α4,1	0.04386	−0.4518	−0.02878	−0.05007	−1.154	0.0642
α4,4	1.007	1.035	0.9609	1.088	0.9964	0.9234
α5,4	0.02466	−0.00941	−0.04889	0.01455	0.0166	0.01825
α5,5	0.9195	0.9364	0.9619	1.009	0.8492	1.038
α6,5	−0.01429	−0.01426	0.01484	−0.03123	0.003516	0.1004
α6,6	0.9076	0.9634	0.9975	0.9633	0.9813	0.9205
α7,7	0.9559	0.9505	0.8771	−0.003746	0.9712	0.9715
α7,8	−0.008813	0.116	−0.03773	0.9206	−0.0272	−0.008996
α8,1	0.04043	0.08352	−0.06336	−0.06863	−0.4614	−0.03286
α8,8	1.004	0.95	0.9101	0.9299	0.838	0.9771
α9,1	0.01675	−0.02692	0.1083	−0.03747	0.2844	0.004906
α9,9	0.9792	0.9774	0.9507	0.894	0.9698	0 0.9758
α10,9	−0.008387	0.02753	0.004947	0.003376	−0.009407	−0.05058
α10,10	0.9849	0.9891	1.034	1.003	1.01	0.8575
α11,1	0.004463	−0.02747	0.08688	−0.01919	−0.2498	−0.009152
α11,11	0.9275	0.9473	0.973	0.96	0.9991	0.9859
α12,11	0.4629	0.4408	0.03193	0.006276	−0.07244	−0.004912
α12,12	0.4629	0.4408	0.9559	1.006	0.9513	0.9308
α13,12	0.04349	−0.5637	0.004907	0.002787	0.0072	−0.04064
α13,13	0.9519	0.8627	1	0.9959	0.9985	0.9816
α14,1	0.02952	−0.05729	−0.005054	0.01943	0.05795	0.1241
α14,14	1.009	1.052	1.004	1	0.9891	0.6846
α15,14	−0.02022	0.01556	−0.03691	−0.05527	0.03189	−0.0311
α15,15	0.9266	0.8891	0.8629	0.9462	1.004	0.9938
α16,1	−0.0004636	−0.04371	0.3009	0.0124	0.2117	0.046
α16,13	−0.005901	−0.0002026	0.103	0.01417	−0.1269	−0.05952
α16,14	−0.01709	0.05491	0.03214	−0.06075	0.07642	−0.07678
α16,16	0.924	1.013	1.045	0.937	0.925	0.9677
β1	0.01208	−0.335	−0.002459	−0.1463	−0.002459	−0.003217
β2	0.1753	0.05707	0.04106	0.04027	0.04106	0.2366
β3	−2.499	−1.083	0.2417	−0.08982	0.2417	−0.1813
β4	−0.01477	0.1958	0.03316	−0.009949	0.03316	0.0329
β5	0.07958	0.04697	0.04301	−0.01343	0.04301	−0.03471
β6	0.06151	0.0233	−0.007604	0.03372	−0.007604	0.002424
β7	0.02485	−0.04106	0.08378	0.04512	0.08378	0.02556
β8	−0.01578	−0.009031	0.07676	0.07833	0.07676	0.05326
β9	0.001499	0.02581	−0.03155	0.07065	−0.03155	0.01194
β10	0.01053	−0.003166	−0.02052	−0.004804	−0.02052	0.0951
β11	0.03175	0.03484	−0.03126	0.03382	−0.03126	0.01811
β12	0.03461	0.04657	0.005745	−0.01031	0.005745	0.0334
β13	0.0001118	0.2914	−0.003158	−0.001051	−0.003158	0.03189
β14	−0.0173	−0.01331	0.003529	−0.01026	0.003529	0.07618
β15	0.04294	0.03025	0.09271	0.04081	0.09271	0.02294
β16	0.04687	−0.02949	−0.2458	0.05101	−0.2458	0.07875