FIG. 8.

ghrelin^−/− mice exhibit normal susceptibility to diet-induced obesity. Twenty-week-old mice were fed either a high-fat (A) or a high-protein (B) diet for 10 weeks. M, male (n = 7); F, female (n = 7). Body weight, P > 0.05 for +/+ versus −/− animals of the same sex on each diet. (C) Body composition after 10 weeks on normal, high-fat, and high-protein diets. Males, **, P < 0.001 high-fat versus normal and high-protein diets; females, *, P < 0.05 high-fat versus normal and high-protein diets. P > 0.05 for +/+ versus −/− animals within each diet.