TABLE 3.
Phenotype | Mean % ± SD (na) determined in laboratory:
|
Largest mean/ smallest mean | P value | ||||
---|---|---|---|---|---|---|---|
A | B | Cb | D | E | |||
CD4+ | 47.1 ± 9.8 (44) | 46.9 ± 11.3 (44) | 48.8 ± 10.5 (44) | 46.7 ± 10.0 (43) | 47.1 ± 10.8 (43) | 1.04 | 0.06 |
CD8+ | 24.1 ± 9.2 (44) | 20.1 ± 7.9 (44) | 24.9 ± 9.2 (44) | 19.7 ± 6.85 (43) | 18.7 ± 6.7 (43) | 1.33 | <0.0001 |
CD26+ CD3+ | 45.6 ± 10.7 (44) | 54.4 ± 10.1 (41) | 45.2 ± 17.0 (44) | 52.7 ± 13.0 (43) | 46.2 ± 9.94 (43) | 1.20 | 0.001 |
CD26+ CD4+ | 35.1 ± 9.1 (44) | 38.7 ± 10.0 (41) | 38.0 ± 10.2 (43) | 34.2 ± 9.61 (43) | 1.13 | <0.0001 | |
CD26+ CD8+ | 10.5 ± 4.7 (44) | 15.7 ± 6.2 (41) | 14.7 ± 6.27 (43) | 12.0 ± 4.98 (43) | 1.50 | <0.0001 | |
CD25+ CD3+ | 3.4 ± 1.6 (44) | 30.7 ± 11.3 (41) | 10.8 ± 7.4 (44) | 38.5 ± 12.4 (43) | 13.8 ± 7.28 (43) | 11.4 | <0.0001 |
CD25+ CD4+ | 3.1 ± 1.5 (44) | 21.0 ± 9.8 (41) | 25.8 ± 8.97 (43) | 10.3 ± 4.38 (43) | 8.4 | <0.0001 | |
CD25+ CD8+ | 1.0 ± 0.2 (18) | 9.7 ± 5.4 (41) | 12.6 ± 6.71 (43) | 3.49 ± 4.33 (43) | 12.1 | <0.0001 | |
DR+ CD4+ | 4.03 ± 1.4 (44) | 4.0 ± 1.7 (41) | 4.60 ± 1.75 (43) | 3.04 ± 1.36 (43) | 1.51 | <0.0001 | |
DR+ CD8+ | 5.6 ± 4.6 (43) | 7.0 ± 7.1 (41) | 9.5 ± 10.1 (44) | 6.35 ± 4.51 (43) | 4.61 ± 5.26 (43) | 2.05 | <0.0001 |
CD38+ CD4+ | 22.6 ± 7.7 (44) | 24.7 ± 12.0 (41) | 30.3 ± 9.05 (43) | 25.0 ± 8.67 (43) | 1.34 | 0.0005 | |
CD38+ CD8+ | 9.94 ± 4.4 (44) | 8.56 ± 4.9 (41) | 14.2 ± 6.2 (43) | 9.60 ± 5.32 (43) | 6.04 ± 3.82 (43) | 2.35 | <0.0001 |
Number of patients analyzed at the laboratory. In almost all cases, two replicates per subject were analyzed for each phenotype at each laboratory; occasionally, only one replicate per patient was analyzed.
Laboratory C did not measure CD26+ CD4+, CD26+ CD8+, CD25+ CD8+, CD25+ CD4+, DR+ CD4+, and CD38+ CD4+ cells.