TABLE 4.
Comparisons of T-cell subsets by disease group
| Phenotype | Mean % ± SD (na) in:
|
Largest mean/smallest mean | P valueb | |
|---|---|---|---|---|
| Healthy group | Group with immunological disease | |||
| CD4+ | 47.9 ± 7.13 (225) | 43.6 ± 17.0 (130) | 1.13 | 0.13 |
| CD8+ | 19.6 ± 5.67 (225) | 24.6 ± 12.0 (130) | 1.29 | 0.03 |
| CD26+ CD3+ | 45.9 ± 10.7 (221) | 46.7 ± 17.8 (127) | 1.13 | 0.47 |
| CD26+ CD4+ | 35.8 ± 7.98 (183) | 31.8 ± 14.2 (103) | 1.25 | 0.83 |
| CD26+ CD8+ | 11.0 ± 3.78 (183) | 14.9 ± 8.23 (104) | 1.35 | 0.04 |
| CD25+ CD3+ | 15.9 ± 13.6 (221) | 18.5 ± 15.7 (127) | 1.40 | 0.03 |
| CD25+ CD4+ | 12.9 ± 10.5 (183) | 13.8 ± 10.8 (103) | 1.26 | 0.07 |
| CD25+ CD8+ | 4.74 ± 5.50 (157) | 7.61 ± 7.60 (89) | 1.93 | 0.15 |
| DR+ CD4+ | 3.25 ± 1.13 (183) | 4.30 ± 2.26 (104) | 1.10 | 0.76 |
| DR+ CD8+ | 3.90 ± 2.82 (218) | 10.6 ± 10.7 (125) | 2.71 | 0.007 |
| CD38+ CD4+ | 27.3 ± 9.13 (183) | 21.8 ± 11.8 (104) | 1.25 | 0.84 |
| CD38+ CD8+ | 8.70 ± 4.67 (221) | 12.2 ± 7.11 (125) | 1.68 | 0.006 |
a
Number of patient replicates analyzed.
b
Based on comparison of all three study disease groups, including putative MCS.