TABLE 5.
Presence of specific IgM and IgG antibodies in patients with acute and persistent brucellosis
| Stage of illnessa | No. of patients with positive result (% positive, 95% CI) in the indicated assay
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| SAT, ≥1:320 | SAT, ≥1:160 | SAT-DTT, ≥1:160 | SAT-DTT, ≥1:80 | SAT-DTT, ≥4-fold titer reduction | Coombs, ≥1:320 | IgM flow, ≥1+ | IgG flow, ≥1+ | IgM + IgG flow, ≥1+b | |
| Acute (n = 23) | 16 (70, 47-86) | 20 (87, 65-97) | 11 (48, 27-69) | 13 (57, 35-76) | 15 (65, 43-83) | 23 (100, 82-100) | 14 (61, 39-80) | 17 (74, 51-89) | 21 (91, 71-99) |
| Persistent (n = 13) | 7 (54, 26-80) | 9 (69, 39-90) | 3 (23, 6-54) | 5 (39, 15-68) | 5 (39, 15-68) | 13 (100, 72-100) | 4 (31, 10-61) | 10 (77, 46-94) | 12 (92, 62-100) |
a
Acute, <3 months of illness at diagnosis; persistent, >3 months of illness at diagnosis.
b
Positive (≥1+) test result in at least one of the two flow assays.