TABLE 2.
Diagnostic performance of OIA for detection of vaginal carriage of GBS compared to culture in women with light, heavy, and dense GBS colonization (n = 1,306)
| GBS colonization levela | Performance characteristicb
|
|||
|---|---|---|---|---|
| Sensitivity | Specificity | Positive predictive value | Negative predictive value | |
| Light | 13.3 (7.1, 22.9) | 98.4 (97.5, 99.0) | 37.9 (21.3, 57.6) | 94.1 (92.5, 95.3) |
| Heavy | 41.5 (29.7, 54.4) | 97.7 (96.6, 98.4) | 48.2 (34.8, 61.8) | 97.0 (95.8, 97.8) |
| Dense | 68.4 (43.5, 86.4) | 96.5 (95.2, 97.5) | 24.5 (14.2, 38.6) | 99.5 (98.8, 99.8) |
a
The GBS colonization levels were defined as follows: light, isolation of GBS from Lim broth alone; heavy, isolation of GBS from either urine or direct plating on blood agar; dense, growth in the third or fourth quadrant streaked on the blood agar plate (14).
b
The four performance characteristics, sensitivity, specificity, and positive and negative predictive values, are all given as percentages. The 95% CIs are given in parentheses.