TABLE 5.

Summary of comparison between ELMA and sequencing results for clinical samples

Enzyme targeted	Codon	No. of samples	No. of samples for which the following combination of resultsa was obtained:									Sensitivityb	Specificityc
			a	b	c	d	e	f	g	h	i
RT	41	43	21	14	1	3	0	2	1	1	0	0.947	0.955
	67	44	20	10	3	5	0	6	0	0	0	1.000	1.000
	70	44	36	4	0	0	0	3	0	0	1	0.800	1.000
	184	42	20	18	0	1	1	1	0	2	0	0.909	1.000
	215	31	10	18	0	0	1	1	0	1	0	0.950	1.000
Protease	30	38	22	11	0	0	0	2	0	1	2	0.786	1.000
	46	45	30	8	3	0	1	1	1	1	0	0.923	0.968
	48	45	44	0	1	0	0	0	0	0	0	1.000	1.000
	82	43	36	5	1	0	0	0	0	1	0	0.857	1.000
	84	45	41	3	0	0	0	0	1	0	0	1.000	0.976
	90	45	23	18	1	1	1	0	1	0	0	1.000	0.958

^aa, wild type by both ELMA and sequencing; b, mutant by both methods; c, mixture by both methods; d, mixture by ELMA and mutant by sequencing; e, mutant by ELMA and mixture by sequencing; f; mixture by ELMA and wild type by sequencing; g, mutant by ELMA and wild type by sequencing; h, wild type by ELMA and mutant by sequencing; i, wild type by ELMA and mixture by sequencing.

^bCalculated as (b + c + d + e)/(b + c + d + e + h + i).

^cCalculated as a/(a + g).