TABLE 3.
STsa characterized among a global collection of 166 serotype 1 S. pneumoniae isolates
| Genetic lineage | ST | No. of isolates | Yr of isolation | Allelic profile
|
Location(s) where ST was isolated (no. of isolates) | MLST comments | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| aroE | gdh | gki | recP | spi | xpt | ddl | ||||||
| A | 306 | 41 | 1995-2001 | 12 | 8 | 13 | 5 | 16 | 4 | 20 | Europe (39), Canada (1), United States (1) | Major invasive serotype 1 clone in Sweden in the late 1990s |
| 617 | 1 | 2001 | 12 | 64 | 13 | 5 | 16 | 4 | 20 | Europe | Newly recognized ST | |
| 228 | 15 | 1996-2001 | 12 | 8 | 1 | 5 | 17 | 4 | 20 | Europe (12), Canada (3) | Previously noted in Denmark and Spain | |
| 227 | 40 | 1995-2001 | 12 | 5 | 13 | 5 | 17 | 4 | 20 | England (9), Canada (15), United States (14), Europe (2) | Previously noted in the United Kingdom and Denmark | |
| 304 | 10 | 1996-2001 | 13 | 8 | 13 | 5 | 17 | 4 | 8 | Europe (8), Canada (1), United States (1) | Previously noted in Sweden | |
| 305 | 3 | 2000 | 13 | 8 | 13 | 5 | 17 | 4 | 28 | Europe | Previously noted in Sweden | |
| B | 217 | 29 | 1990-2001 | 10 | 18 | 4 | 1 | 7 | 19 | 9 | Africa (13), Israel (11), Europe (5) | Previously noted in Denmark and Sweden |
| 303 | 1 | 2001 | 10 | 5 | 4 | 1 | 7 | 19 | 9 | United States | Single-locus variant of ST217; previously noted in Sweden | |
| 614 | 3 | 2001 | 10 | 18 | 4 | 1 | 3 | 19 | 9 | Africa | Single-locus variant of ST217 | |
| 612 | 4 | 1998-2001 | 10 | 18 | 4 | 1 | 7 | 19 | 31 | Africa (3), Israel (1) | Single-locus variant of ST217 | |
| 613 | 1 | 2001 | 10 | 18 | 4 | 1 | 7 | 19 | 1 | Africa | Single-locus variant of ST217 | |
| 618 | 1 | Unknown | 13 | 8 | 4 | 1 | 7 | 19 | 14 | Europe | Newly recognized ST | |
| C | 615 | 12 | 2000-2001 | 10 | 31 | 4 | 1 | 6 | 4 | 94 | Chile (11), United States (1) | ST of the 1948 serotype 1 reference strain |
| 611 | 2 | 2001 | 10 | 9 | 4 | 1 | 6 | 4 | 94 | Africa | Single-locus variant of ST615 | |
| 616 | 2 | 1995-1996 | 10 | 31 | 4 | 1 | 62 | 4 | 94 | Europe | Single-locus variant of ST615 | |
| 300 | 1 | 2001 | 10 | 31 | 4 | 34 | 6 | 4 | 5 | England | Double-locus variant of ST615; previously noted in Sweden | |
A total of 16 STs were found.