. Author manuscript; available in PMC: 2009 Jan 13.

Published in final edited form as: Org Lett. 2006 Oct 12;8(21):4695–4697. doi: 10.1021/ol061569t

Table 1.

Trans/Cis Ratios (CDCl₃) and σ_p Values of X in Fm–Pro–OC₆H₄-p-X at 25 °C.

X	σ_p^a	K_trans/cis	ΔG (kcal/mol)^b
NO₂	0.78	4.13 ± 0.05	−0.84
CN	0.66	3.95 ± 0.03	−0.81
H	0.00	2.120 ± 0.005	−0.45
OMe	−0.27	2.01 ± 0.04	−0.41
NMe₂	−0.83	1.67 ± 0.02	−0.30

From ref. 6.

ΔG = –RTlnK_trans/cis.