. Author manuscript; available in PMC: 2009 Jan 13.

Published in final edited form as: J Med Chem. 2007 Apr 10;50(9):2078–2088. doi: 10.1021/jm061398y

Table 2.

Tissue Concentrations of ¹¹C-labeled Compounds at T = 30 min in Rats ^a

compd	ventricle left	lung	liver	spleen	muscle	adrenal medulla	blood
[¹¹C]HED	2.85 ± 0.42	0.40 ± 0.12	2.32 ± 0.25	1.31 ± 0.14	0.17 ± 0.02	0.72 ± 0.08	0.08 ± 0.01
[¹¹C]EPI	2.14 ± 0.32	0.39 ± 0.05	1.95 ± 0.16	0.64 ± 0.02	0.22 ± 0.03	0.61 ± 0.18	0.13 ± 0.01
[¹¹C]1b	2.28 ± 0.12	0.74 ± 0.15	0.89 ± 0.13	0.63 ± 0.16	0.07 ± 0.01	0.88 ± 0.15	0.07 ± 0.01
[¹¹C]1c	3.30 ± 0.28	0.68 ± 0.16	0.84 ± 0.21	0.97 ± 0.06	0.14 ± 0.04	1.17 ± 0.16	0.16 ± 0.01
[¹¹C]1d	1.91 ± 0.16	0.86 ± 0.11	3.91 ± 0.23	0.88 ± 0.07	0.10 ± 0.03	0.53 ± 0.07	0.09 ± 0.01
[¹¹C]1e	1.17 ± 0.14	0.75 ± 0.10	2.71 ± 0.36	0.63 ± 0.10	0.07 ± 0.01	0.36 ± 0.06	0.14 ± 0.01
[¹¹C]1j	1.77 ± 0.27	0.56 ± 0.15	1.22 ± 0.18	0.52 ± 0.10	0.07 ± 0.01	0.56 ± 0.21	0.08 ± 0.01
[¹¹C]1k	1.01 ± 0.12	0.34 ± 0.06	0.92 ± 0.07	0.43 ± 0.12	0.06 ± 0.01	0.46 ± 0.07	0.07 ± 0.01

Values are % injected dose/g; mean ± standard deviation of five determinations.