Table 2.

Sleep Data at Baseline and 3 Months after Randomization

	Control group (n = 108)		CPAP treated group (n = 97)		Between group P-value
	Baseline	3 months	Baseline	3 months
Effect on CSA
Total AHI, no/h	37.8 ± 15.1	37.6 ± 25.7	38.9 ± 15.0	17.6 ± 16.3*	< 0.001
Central AHI, no/h	33.0 ± 15.0	30.7 ± 23.6	35.4 ± 15.1	16.1 ± 16.3*	< 0.001
Obstructive AHI, no/h	4.8 ± 4.9	6.9 ± 10.7	3.5 ± 4.1	1.6 ± 3.9*	< 0.001
Mean SaO2, %	93.1 ± 3.3	93.5 ± 2.8†	93.2 ± 3.6	94.9 ± 2.7*	< 0.001
Lowest SaO2, %	81.9 ± 6.3	83.0 ± 6.0†	81.4 ± 8.1	86.3 ± 6.4*	< 0.001
Effect on Arousals
Arousal index, no/h	24.8 ± 19.3	26.3 ± 18.6	28.8 ± 23.7	24.3 ± 19.5	0.15
Effect on Sleep Structure
Time in bed, min	452.4 ± 51.4	457.5 ± 48.9	454.5 ± 51.7	454.5 ± 44.9	0.49
Sleep period time, min	421.4 ± 52.7	423.7 ± 55.9	428.8 ± 54.4	423.7 ± 48.7	0.57
Total sleep time, min	310.5 ± 84.3	308.9 ± 77.6	318.2 ± 75.6	318.0 ± 73.9	0.55
Sleep efficiency, %	68.4 ± 16.5	67.8 ± 16.6	70.3 ± 16.4	70.2 ± 15.7	0.45
Sleep onset latency, min	30.8 ± 30.5	33.7 ± 36.	25.3 ± 27.7	30.6 ± 29.3	0.99
Wake after sleep onset, min	111.0 ± 65.4	114.8 ± 70.0	110.6 ± 70	105.7 ± 65.5	0.29
Stage 1 percentage, %	18.2 ± 12.8	18.9 ± 12.9	19.1 ± 13.5	16.8 ± 15.3	0.14
Stage 2 percentage, %	58.8 ± 13.5	58.0 ± 14.4	56.6 ± 15.5	59.0 ± 15.3	0.27
SWS percentage, %	9.6 ± 11.0	10.3 ± 10.8	10.8 ± 10.1	10.8 ± 11.7	0.77
REM sleep percentage, %	13.1 ± 6.8	12.7 ± 7.9	13.6 ± 7.0	13.3 ± 7.0	0.69
PLMI, no/h	25.8 ± 38.9	24.1 ± 33.2	24.9 ± 40.4	26.4 ± 38.7	0.48

Values are expressed as means ± SD.

Abbreviations: AHI = apnea-hypopnea index, CSA = central sleep apnea, PLMI = periodic leg movement index, SaO₂ = oxygen saturation, SWS = slow wave sleep;

^*P < 0.001 compared to their baseline;

^†P = 0.04 compared to their baseline