TABLE 1.
Properties of the 10 DNA fragments used for C. albicans MLST
| Gene fragment | C. albicans chromo- somea | No. of bases analyzed | No. of variable bases
|
dN/dSc | No. of Genotypes
|
||
|---|---|---|---|---|---|---|---|
| This study | Previous study (4)b | Found | Per vari -able base | ||||
| AAT1a | 2 | 373 | 10 | 7 | 0.17 | 23 | 2.3 |
| AAT1b | 2 | 339 | 6 | 6 | 0.08 | 15 | 2.5 |
| ACC1 | 3 | 407 | 7 | 6 | 0.20 | 15 | 2.1 |
| ADP1 | 1 | 443 | 16 | 15 | 0.41 | 23 | 1.4 |
| GLN4 | 3 | 404 | 11 | 11 | 1.00 | 20 | 1.8 |
| MPIb | 2 | 375 | 11 | 11 | 0.33 | 20 | 1.8 |
| RPN2 | 1 | 306 | 13 | 11 | 0.11 | 20 | 1.5 |
| SYA1 | 6 | 391 | 13 | 13 | 0.34 | 26 | 2.0 |
| VPS13 | 4 | 403 | 17 | 16 | 0.70 | 38 | 2.2 |
| ZWF1b | 1 | 491 | 9 | 8 | 0.12 | 36 | 4.0 |
a
Tentative assignment of the chromosome on which the fragment is located, from http://cbr-rbc.nrc-cnrc.gc.ca/biovis/candida/.
b
The number of variable bases has increased because of the larger panel of isolates sequenced.
c
Calculated according to Nei and Gojobori (3).