TABLE 1.
Experiment schema for analysis of plasmid combinations in micea
| Vaccine | Plasmid | Amt (μg) |
|---|---|---|
| VR1012 | 1012 | 50 μg |
| ABC(×4) | 1012-A-gp145ΔCFI | 8.3 μg |
| 1012-B-gp145ΔCFI | 8.3 μg | |
| 1012-C-gp145ΔCFI | 8.3 μg | |
| 1012-B-gag-pol-nef | 25 μg | |
| ABC(×6) | 1012-A-gp145ΔCFI | 8.3 μg |
| 1012-B-gp145ΔCFI | 8.3 μg | |
| 1012-C-gp145ΔCFI | 8.3 μg | |
| 1012-A-gag-pol-nef | 8.3 μg | |
| 1012-B-gag-pol-nef | 8.3 μg | |
| 1012-C-gag-pol-nef | 8.3 μg |
a
Different combinations of plasmids were tested in groups of 10 mice each. The first, second, and third immunizations were carried out at weeks 0, 2, and 6, and ICC was performed on spleen cells at week 7.