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CD8+ T cells isolated from mice treated with pCCR7L have the capacity to produce more IFN-γ than CD8+ T cells from non-pCCR7L-treated mice. IFN-γ secretion by CD8+ T cells isolated from spleen, MLN, and genital tract was assessed by in vitro stimulation with splenocytes pulsed with gB498-505 in ELISPOT assays. CD8+ T cells were examined at 14 (A; acute phase) and 60 days (B; memory phase) after boost. Data are from a representative experiment of two performed.
