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. Author manuscript; available in PMC: 2009 Jun 5.
Published in final edited form as: Virology. 2008 Mar 19;375(2):637–645. doi: 10.1016/j.virol.2008.02.017

FIGURE 1.

FIGURE 1

Schematic of the 524 a.a. Gag protein (bp 4231-5805) present in the high infectious titer proviral clone PERV-A14/220 (Harrison et al., 2004). Processed Gag components [Matrix (MA), Capsid (CA) and Nucleocapsid (NC)] are delineated based on similarity to MLV Gag sequences. The two L domain motifs, PPPY and PFAP, reside in p12 and are underlined. Mutations were introduced into the L domains by site-directed mutagenesis. Resulting amino acid sequences are shown for each construct used to evaluate the role of the L domains.