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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Cell Death Differ. 2008 Oct 24;16(2):287–297. doi: 10.1038/cdd.2008.153

Figure 6.

Figure 6

Haploinsufficiency of RanBP2 renders 24-week old mice refractory to gain of body weight and epididymal fat mass when placed on a high-fat (40%) diet. RanBP2+/+ but not RanBP2+/− mice gain significant body weight (a) and epididymal fat mass (b) when placed on a high-fat diet for 12 weeks. In (a) double asterisks represent significant differences between the groups (Student’s t test, P=0.05). Statistical significance was also found across the time-course of the experiment (repeated measures 2-way ANOVA, P=0.03). Results shown represent the mean ± S.D. (n=4).