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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Cytokine. 2008 Aug 15;44(1):101–107. doi: 10.1016/j.cyto.2008.06.010

Figure 2. IL-21 induces upregulation of cytokine and chemokine production.

Figure 2

Figure 2

Human monocytes (2A, 2C) or U937 cells (2B, 2D) (30 × 106 cells) were incubated with orthovanadate (5mM) for 30 minutes, and either untreated or stimulated with IL-21 (50 ng/mL) for 6 hours. Supernatants from each sample were incubated with the cytokine/chemokine antibody array for two hours before development using streptavidin-HRP solution. Data represents the mean ± SD of three experiments. (A, C) * Monocytes P < 0.05, (B, D) * U937 P < 0.01.