Studies in WT mice: Retinal function measurements were recorded from WT C57BL/6J mice treated with TUDCA or vehicle from P6 to P30. A) Representative dark-adapted ERG waveforms for WT TUDCA- and vehicle-treated mice. Dark-adapted a-wave (B), dark-adapted b-wave (C) or light-adapted b-wave (D) amplitudes from WT mice treated with TUDCA (n=5) or vehicle (n=2) show no differences in amplitude or timing across different flash intensities [Repeated measures ANOVA F(4, 20) = 2.020, p = 0.130; F(4, 20) = 3.110, p = 0.138; F(6, 30)=0.532, p = 0.779; respectively]. We concluded that TUDCA treatment from P6 to P30 has no deleterious effect on retinal function, as measured with the ERG.