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. 2008 Oct 22;22(12):2624–2642. doi: 10.1210/me.2008-0157

Figure 7.

Figure 7

Analysis of the hGR −2956/−2916 Sequence

A, The predicted c-Myb, nGRE, and Ets (italicized) binding sequences are bolded and underlined. B, Basal promoter activity [in relative light units (RLU)] and hormonal response of deletion constructs. Shown are 5′-end deletion of the −3530/−2523 hGR sequence, and a further internal deletion of the −2956/−2916 sequence itself. The hormonal response of each individual luciferase reporter construct in Jurkat cells is depicted as the percentage of its respective EtOH control. **, P < 0.01; ***, P < 0.005.